Array cgh and PGS?

Forum for those considering or embarking on Pre-Implantation Genetic Diagnosis or Aneuploidy Screening

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Sofy36
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Joined: Sat May 20, 2017 10:15 am

Array cgh and PGS?

#1 Post by Sofy36 » Sun Jul 09, 2017 3:01 pm

What is the difference between array cgh and PGS?

EastCoaster
Posts: 3
Joined: Tue Aug 01, 2017 9:08 pm

Re: Array cgh and PGS?

#2 Post by EastCoaster » Wed Aug 02, 2017 9:01 pm

Hello, PGS is a generic term for genetic screening that looks for chromosomal abnormalities. Methods of testing include:
NGS (newest)
aCGH
FISH (oldest)

You would have to ask your clinic which test method they use. Here's a scientific article comparing NGS and aCGH. This particular paper finds that NGS is the preferred method.
https://bmcmedgenomics.biomedcentral.co ... 015-0110-4

Note that there is also PGD which is a term for genetic screening that looks for particular "bad things" like fatal diseases. But unless you are a known carrier for a disease, you would do PGS. PGS can detect monosomies or trisomies in otherwise good-looking embryos, and which would cause miscarriage or failure to implant.

Just the usual caution that am not a doctor :-) but I did a lot of research on PGS when we started IVF because I had a miscarriage recently due to blighted ovum which can be caused by chromosomal abnormality. I decided to do PGS because I am older (37) so at higher risk and I don't want to go through another miscarriage if I can help it.

Hope that helps :-)
Marie

Me&IVF
Posts: 5
Joined: Thu Nov 29, 2018 2:47 pm

Re: Array cgh and PGS?

#3 Post by Me&IVF » Fri Nov 22, 2019 9:01 am

With array test, can we determine the sex of the baby?

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